33803-42-8
33803-42-8
Chemical Structure
Gnaphaliin
- CAS. Nr.: 33803-42-8
- Formula:C17H14O6
- Molecular Weight:314.29
IUPAC Name: 5,7-dihydroxy-3,8-dimethoxy-2-phenyl-4H-chromen-4-one
InChIKey: OWQLBLNRUZULFV-UHFFFAOYSA-N
SMILES: O=C1C(OC)=C(C2=CC=CC=C2)OC3=C1C(O)=CC(O)=C3OC
Biological Activity: Gnaphaliin is a flavonoid compound that exerts antioxidant, anti-inflammatory, and tracheal smooth muscle relaxant effects by inhibiting lipid peroxidation, scavenging free radicals, chelating trace elements, and reducing neutrophil infiltration. Gnaphaliin can be used in research on asthma, inflammation, and atherosclerosis[1][2][3][4][5][6].
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Gnaphaliin | Gnaphaliin is a flavonoid compound that exerts antioxidant, anti-inflammatory, and tracheal smooth muscle relaxant effects by inhibiting lipid peroxidation, scavenging free radicals, chelating trace elements, and reducing neutrophil infiltration. Gnaphaliin can be used in research on asthma, inflammation, and atherosclerosis. | |||||||||||||||||||||
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References
- [1]. Rodríguez-Ramos F, et al. Solving the confusion of gnaphaliin structure: gnaphaliin A and gnaphaliin B identified as active principles of Gnaphalium liebmannii with tracheal smooth muscle relaxant properties. Journal of natural products. 2009 Jun;72(6):1061-4.
- [2]. Sala A, et al. Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside. European journal of pharmacology. 2003 Feb 07;461(1):53-61.
- [3]. Schinella GR, et al. Tiliroside and gnaphaliin inhibit human low density lipoprotein oxidation. Fitoterapia. 2007 Jan;78(1):1-6.
- [4]. Demarque DP, et al. Optimization and technological development strategies of an antimicrobial extract from Achyrocline alata assisted by statistical design. PloS one. 2015;10(2):e0118574.
- [5]. Pedro Cuadra, et al. Increases in surface flavonols and photosynthetic pigments in Gnaphalium luteo-album in response to UV-B radiation, Phytochemistry, Volume 45, Issue 7, 1997, Pages 1377-1383, ISSN 0031-9422.
- [6]. Sánchez I, et al. In vitro cytotoxicity of flavonoids against MK2 and C6 tumour cells. Phytotherapy research : PTR. 2001 Jun;15(4):290-3.
