371242-53-4
371242-53-4
Chemical Structure
PIK-39
- CAS No.: 371242-53-4
- Formula:C21H15ClN6O2S
- Molecular Weight:450.90
IUPAC Name: 2-(((9H-purin-6-yl)thio)methyl)-5-chloro-3-(2-methoxyphenyl)quinazolin-4(3H)-one
InChIKey: UMMYTDJYDSTEMB-UHFFFAOYSA-N
SMILES: O=C1N(C(CSC2=C3N=CNC3=NC=N2)=NC4=C1C(Cl)=CC=C4)C5=CC=CC=C5OC
Biological Activity: PIK-39 is a selective PI3Kδ inhibitor with an IC50 of 0.30 μM. PIK-39 has a propeller-like structure that induces conformational changes in the ATP-binding region of its target. PIK-39 is applicable to the research of autoimmune diseases[1].
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PIK-39 | PIK-39 is a selective PI3Kδ inhibitor with an IC50 of 0.30 μM. PIK-39 has a propeller-like structure that induces conformational changes in the ATP-binding region of its target. PIK-39 is applicable to the research of autoimmune diseases. | |||||||||||||||||||||
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References
Keywords
