37326-33-3
Chemical Structure
Hyaluronidase, Bovine testes
Synonym(s): Hyaluronate 4-glycanohydrolase, Bovine testes; Hyaluronoglucosaminidase, Bovine testes
- CAS No.: 37326-33-3
- Molecular Weight:55000 (average)
SMILES: [Hyaluronidase, Bovine testes]
Biological Activity: Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid (HA) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection[1][2][3][4][5][6].
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Hyaluronidase, Bovine testes | Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid (HA) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection. | |||||||||||||||||||||
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Hyaluronidase (human recombinant) | Hyaluronidase (human recombinant) (Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media. | |||||||||||||||||||||
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Hyaluronidase (GMP like) | Hyaluronidase (GMP like) is a GMP-compliant version of hyaluronidase. Hyaluronidase is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase can be used to improve the absorption and dispersion of parenteral fluids, medications, and contrast agents. | |||||||||||||||||||||
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Hyaluronidase, Ovine testes | 95.00% | Hyaluronidase, Ovine testes is an endoglycosidase. Hyaluronidase, Ovine testes specifically degrades Hyaluronic acid (HY-B0633A) and Chondroitin sulfate (HY-B2162) by hydrolyzing β-glycosidic bonds in acidic mucopolysaccharides. Hyaluronidase, Ovine testes disperses follicular cells during fertilization by breaking down the hyaluronic acid-rich cumulus. Hyaluronidase, Ovine testes can be used in the study of fertility-related diseases. | ||||||||||||||||||||
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References
- [1]. Vartanian AJ, et al. Injected hyaluronidase reduces restylane-mediated cutaneous augmentation. Arch Facial Plast Surg. 2005 Jul-Aug;7(4):231-7. [Content Brief]
- [2]. Brandon E, et al. The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature. J Clin Investigat Dermatol. 2015;3(2): 7.
- [3]. Apaza Ticona L, et al. Rubus urticifolius Compounds with Antioxidant Activity, and Inhibition Potential against Tyrosinase, Melanin, Hyaluronidase, Elastase, and Collagenase[J]. Pharmaceuticals (Basel). 2024 Jul 13;17(7):937. [Content Brief]
- [4]. Jung H. Hyaluronidase: An overview of its properties, applications, and side effects[J]. Arch Plast Surg. 2020 Jul;47(4):297-300. [Content Brief]
- [5]. Lee W, et al. Comparative Effectiveness of Different Interventions of Perivascular Hyaluronidase[J]. Plast Reconstr Surg. 2020 Apr;145(4):957-964. [Content Brief]
- [6]. Wang M, et al. Comparison of Intra-arterial and Subcutaneous Testicular Hyaluronidase Injection Treatments and the Vascular Complications of Hyaluronic Acid Filler[J]. Dermatol Surg. 2017 Feb;43(2):246-254. [Content Brief]
