423732-11-0
Chemical Structure
DapL-IN-1
- CAS No.: 423732-11-0
- Formula:C17H15N3O3S
- Molecular Weight:341.38
IUPAC Name: N-(3-(hydrazinecarbonyl)naphthalen-2-yl)benzenesulfonamide
InChIKey: NBSWNEYEAADJGQ-UHFFFAOYSA-N
SMILES: O=S(C1=CC=CC=C1)(NC2=C(C=C3C=CC=CC3=C2)C(NN)=O)=O
Biological Activity: DapL-IN-1 is an inhibitor of L,L-diaminoheptanoic acid aminotransferase (DapL) with the characteristics of inhibiting DapL activity in bacteria and plants. DapL-IN-1 can be used to design and discover new biocides such as antibiotics, herbicides or algaecides with the potential to be non-toxic to animals. DapL-IN-1 shows differential sensitivity in inhibiting different DapL homologues, which can provide important information for further drug development. DapL-IN-1 may affect its biological activity by affecting the interaction with residues adjacent to the active site, which may lead to different binding modes[1].
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DapL-IN-1 | DapL-IN-1 is an inhibitor of L,L-diaminoheptanoic acid aminotransferase (DapL) with the characteristics of inhibiting DapL activity in bacteria and plants. DapL-IN-1 can be used to design and discover new biocides such as antibiotics, herbicides or algaecides with the potential to be non-toxic to animals. DapL-IN-1 shows differential sensitivity in inhibiting different DapL homologues, which can provide important information for further drug development. DapL-IN-1 may affect its biological activity by affecting the interaction with residues adjacent to the active site, which may lead to different binding modes. | |||||||||||||||||||||
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Keywords
