4329-75-3

N'-Isonicotinoylisonicotinohydrazide Chemical Structure
4329-75-3

Chemical Structure

N'-Isonicotinoylisonicotinohydrazide

Synonym(s): 1,2-Diisonicotinoylhydrazine

  • CAS No.: 4329-75-3
  • Formula:C12H10N4O2
  • Molecular Weight:242.23

IUPAC Name: 2-amino-2-(naphthalen-2-yl)acetic acid hydrochloride

InChIKey: HDADCMZPLLONGB-UHFFFAOYSA-N

SMILES: O=C(C1=CC=NC=C1)NNC(C2=CC=NC=C2)=O

Biological Activity: N'-Isonicotinoylisonicotinohydrazide (Compound 7, 1,2-Diisonicotinoylhydrazine) is a competitive inhibitor (IC50=5-30 μM) of bacterial heme oxygenase (HO). N'-Isonicotinoylisonicotinohydrazide inhibits iron release and bacterial iron acquisition. N'-Isonicotinoylisonicotinohydrazide exhibits selective activity against HO enzymes from Pseudomonas aeruginosa and Neisseria meningitidis. N'-Isonicotinoylisonicotinohydrazide is promising for research of multidrug-resistant Gram-negative bacterial infections[1][2].

Cat. No. Product Name Purity Description Pricing
HY-W354203 		N'-Isonicotinoylisonicotinohydrazide N'-Isonicotinoylisonicotinohydrazide (Compound 7, 1,2-Diisonicotinoylhydrazine) is a competitive inhibitor (IC50=5-30 μM) of bacterial heme oxygenase (HO). N'-Isonicotinoylisonicotinohydrazide inhibits iron release and bacterial iron acquisition. N'-Isonicotinoylisonicotinohydrazide exhibits selective activity against HO enzymes from Pseudomonas aeruginosa and Neisseria meningitidis. N'-Isonicotinoylisonicotinohydrazide is promising for research of multidrug-resistant Gram-negative bacterial infections.
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