4753-03-1
4753-03-1
Chemical Structure
2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine
- CAS No.: 4753-03-1
- Formula:C9H11IN2O5
- Molecular Weight:354.10
IUPAC Name: 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-iodotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: KVQOKCWRUQHGQR-XVFCMESISA-N
SMILES: OC[C@@H]1[C@@H](O)[C@@H](I)[C@H](N2C(NC(C=C2)=O)=O)O1
Biological Activity: 2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine | 2’-Deoxy-2’-iodouridine; 2’-Iodo-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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