479-54-9
Chemical Structure
4',5,7,8-Tetrahydroxyflavanone
Synonym(s): Carthamidin
- CAS No.: 479-54-9
- Formula:C15H12O6
- Molecular Weight:288.25
InChIKey: NPLTVGMLNDMOQE-NSHDSACASA-N
SMILES: O=C1C2=C(O)C(O)=C(O)C=C2O[C@H](C3=CC=C(C=C3)O)C1
Biological Activity: 4',5,7,8-Tetrahydroxyflavanone (Carthamidin) is a flavanone pigment. 4',5,7,8-Tetrahydroxyflavanone can be found in Carthamus tinctorius. 4',5,7,8-Tetrahydroxyflavanone induces ROS generation, oxidative stress, Apoptosis-mediated cell death, cell cycle arrest at G0/G1 phase, mitochondrial membrane potential collapse, and LDH leakage. 4',5,7,8-Tetrahydroxyflavanone exhibits anti-inflammatory, antioxidant, and neuroprotective effects, and acts as a reducing and capping agent for gold nanoparticles. 4',5,7,8-Tetrahydroxyflavanone can be used in breast cancer research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4',5,7,8-Tetrahydroxyflavanone | 96.25% | 4',5,7,8-Tetrahydroxyflavanone (Carthamidin) is a flavanone pigment. 4',5,7,8-Tetrahydroxyflavanone can be found in Carthamus tinctorius. 4',5,7,8-Tetrahydroxyflavanone induces ROS generation, oxidative stress, Apoptosis-mediated cell death, cell cycle arrest at G0/G1 phase, mitochondrial membrane potential collapse, and LDH leakage. 4',5,7,8-Tetrahydroxyflavanone exhibits anti-inflammatory, antioxidant, and neuroprotective effects, and acts as a reducing and capping agent for gold nanoparticles. 4',5,7,8-Tetrahydroxyflavanone can be used in breast cancer research. | ||||||||||||||||||||
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References
- [1]. Palani S, et al. Apoptotic and Molecular Mechanisms of Carthamidin in Breast Cancer Therapy: An Integrated In Vitro and In Silico Study. Molecular biotechnology. 2025 Dec;67(12):4527-4541.
- [2]. Joseph J, et al. Anti-proliferative activities of Carthamidin mediated gold nanoparticles against breast cancer: an in-vitro approach[J]. Nano-Structures & Nano-Objects, 2024, 39: 101324.
- [3]. Özpeynirci A, et al. Safflower flower extracted carthamidin color pigment purification by adsorption chromatography and investigation of its use as a coloring agent in some foods[J]. Microchemical Journal, 2025: 116265.
