491851-53-7
Chemical Structure
Hemokinin 1, human
- No. CAS: 491851-53-7
- Formula:C54H84N14O14S
- Molecular Weight:1185.40
IUPAC Name: (S)-2-((2S,5S,8S,14S,15R)-14-amino-8-(4-aminobutyl)-15-hydroxy-2-(hydroxymethyl)-5-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecanamido)-N1-((5S,8S,14S,17S)-14-benzyl-5-carbamoyl-8-isobutyl-7,10,13,16-tetraoxo-18-phenyl-2-thia-6,9,12,15-tetraazaoctad
InChIKey: NYBLUYYRUFKGTB-XJCFQSCISA-N
SMILES: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CO)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O
Biological Activity: Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia[1][2].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Hemokinin 1, human | 98.11% | Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia. | ||||||||||||||||||||
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References
- [1]. Cai-Yun Fu, et al. Hemokinin-1(4-11)-induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLoS One [Content Brief]
- [2]. Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan;135(1):266-74. [Content Brief]
