524033-40-7
Chemical Structure
NPBA
- CAS No.: 524033-40-7
- Formula:C16H14F3N3O3
- Molecular Weight:353.30
IUPAC Name: N-(2-((4-nitro-2-(trifluoromethyl)phenyl)amino)ethyl)benzamide
InChIKey: LUJDPMMSYZQCHA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1)NCCNC2=CC=C([N+]([O-])=O)C=C2C(F)(F)F
Biological Activity: NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, is a tandem pore domain weak inward rectifying K+ channel (TWIK2) channel blocker. NPBA suppresses NLRP3 inflammasome activation in macrophages[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NPBA | 99.56% | NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, is a tandem pore domain weak inward rectifying K+ channel (TWIK2) channel blocker. NPBA suppresses NLRP3 inflammasome activation in macrophages. | ||||||||||||||||||||
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Keywords