52571-45-6
52571-45-6
Chemical Structure
N4-Benzoyl-2’-O-methylcytidine
- CAS No.: 52571-45-6
- Formula:C17H19N3O6
- Molecular Weight:361.35
IUPAC Name: N-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
InChIKey: LIZIIHWLABYQKD-XKVFNRALSA-N
SMILES: O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)O[C@@H]1CO
Biological Activity: N4-Benzoyl-2’-O-methylcytidine is a natural cytidine nucleoside analog. Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities[1][2].
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N4-Benzoyl-2’-O-methylcytidine | 99.21% | N4-Benzoyl-2’-O-methylcytidine is a natural cytidine nucleoside analog. Cytidine analogs have the mechanism of inhibiting DNA methyltransferase (such as Zebularine (HY-13420)) and have potential antimetabolite and antitumor activities. | ||||||||||||||||||||
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References
- [1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. [Content Brief]
- [2]. Increasing the viability or longevity of an organ or organ explant using modified mRNAs for proteins essential for organ survival. World Intellectual Property Organization, WO2013096709 A2 2013-06-27.
Keywords
