564468-51-5
Chemical Structure
Tubulin polymerization-IN-24
- CAS No.: 564468-51-5
- Formula:C22H16O3
- Molecular Weight:328.36
IUPAC Name: 10-(3-hydroxy-4-methoxybenzylidene)anthracen-9(10H)-one
InChIKey: MQLACMBJVPINKE-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2)/C(C3=CC=CC=C13)=C\C4=CC=C(OC)C(O)=C4
Biological Activity: Tubulin polymerization-IN-24 (compound HMBA) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-24 inhibits MCF-7 cells proliferation. Tubulin polymerization-IN-24 induces apoptosis and cell cycle arrest at G2/M phase. Tubulin polymerization-IN-24 increase the GTP hydrolysis rate and inhibits microtubule assembly[1].
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Tubulin polymerization-IN-24 | Tubulin polymerization-IN-24 (compound HMBA) is a potent tubulin polymerization inhibitor. Tubulin polymerization-IN-24 inhibits MCF-7 cells proliferation. Tubulin polymerization-IN-24 induces apoptosis and cell cycle arrest at G2/M phase. Tubulin polymerization-IN-24 increase the GTP hydrolysis rate and inhibits microtubule assembly. | |||||||||||||||||||||
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Keywords
