57452-97-8
Chemical Structure
(S)-Praziquantel
- CAS No.: 57452-97-8
- Formula:C19H24N2O2
- Molecular Weight:312.41
IUPAC Name: (S)-2-(cyclohexanecarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
InChIKey: FSVJFNAIGNNGKK-QGZVFWFLSA-N
SMILES: O=C1CN(C(C2CCCCC2)=O)C[C@@]3([H])N1CCC4=C3C=CC=C4
Biological Activity: (S)-Praziquantel is an anti-schistosomal compound. (S)-Praziquantel is the inactive S-enantiomer (distomer) of racemic praziquantel, exhibits weaker anthelmintic activity, shows anti-schistosomal activity against S. mansoni and S. japonicum, and can damage the reproductive organs and tegument of S. mansoni worms. (S)-Praziquantel can be used for research on schistosomiasis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(S)-Praziquantel | 99.35% | (S)-Praziquantel is an anti-schistosomal compound. (S)-Praziquantel is the inactive S-enantiomer (distomer) of racemic praziquantel, exhibits weaker anthelmintic activity, shows anti-schistosomal activity against S. mansoni and S. japonicum, and can damage the reproductive organs and tegument of S. mansoni worms. (S)-Praziquantel can be used for research on schistosomiasis. | ||||||||||||||||||||
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(S)-Praziquantel-d11 | 98.23% | (S)-Praziquantel-d11 is the deuterated-labeled (S)-Praziquantel (HY-126057A). (S)-Praziquantel is an anti-schistosomal compound. (S)-Praziquantel is the inactive S-enantiomer (distomer) of racemic praziquantel, exhibits weaker anthelmintic activity, shows anti-schistosomal activity against S. mansoni and S. japonicum, and can damage the reproductive organs and tegument of S. mansoni worms. (S)-Praziquantel can be used for research on schistosomiasis. | ||||||||||||||||||||
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Similarity Score 1.00
HY-126057(R)-Praziquantel -
Similarity Score 1.00
HY-B0244Praziquantel -
Similarity Score 0.90
HY-U00045Epsiprantel -
Similarity Score 0.70
HY-143652Strans-Hydroxy praziquantel-d5 -
Similarity Score 0.61
HY-41656D-Praziquanamine -
Similarity Score 0.61
HY-N1765L-Praziquanamine -
Similarity Score 0.59
HY-126057S(R)-Praziquantel-d11 -
Similarity Score 0.59
HY-B0244SPraziquantel-d11 -
Similarity Score 0.51
HY-151871ICeD-2 -
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References
- [1]. Olliaro P, et al. The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer). The Journal of antimicrobial chemotherapy. 2014 Apr;69(4):863-70. [Content Brief]
- [2]. Wilkins D, et al. Nirsevimab binding-site conservation in respiratory syncytial virus fusion glycoprotein worldwide between 1956 and 2021: an analysis of observational study sequencing data. The Lancet. Infectious diseases. 2023 Jul;23(7):856-866. [Content Brief]
