588691-24-1
Chemical Structure
2’-O-Methyl-5’-O-DMTr-5-iodouridine
Synonym(s): 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine
- No. CAS: 588691-24-1
- Formula:C31H31IN2O8
- Molecular Weight:686.49
IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione
InChIKey: VYNNFLLSYDWMCJ-LTGLEFCMSA-N
SMILES: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](O)[C@@H](OC)[C@H](N5C(NC(C(I)=C5)=O)=O)O4
Biological Activity: 2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-O-Methyl-5’-O-DMTr-5-iodouridine | 2’-O-Methyl-5’-O-DMTr-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
