60398-23-4
60398-23-4
Chemical Structure
6-Iodoamiloride
- CAS No.: 60398-23-4
- Formula:C6H8IN7O
- Molecular Weight:321.08
InChIKey: FKXYVYMLZGVJIM-UHFFFAOYSA-N
SMILES: NC1=C(C(NC(N)=N)=O)N=C(I)C(N)=N1
Biological Activity: 6-Iodoamiloride is a potent acid-sensing ion channel 1 (ASIC1) inhibitor with an IC50 of 88 nM. 6-Iodoamiloride inhibits ASIC3-mediated currents from rat dorsal root ganglion neurons with an IC50 of 230 nM[1].
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6-Iodoamiloride | 6-Iodoamiloride is a potent acid-sensing ion channel 1 (ASIC1) inhibitor with an IC50 of 88 nM. 6-Iodoamiloride inhibits ASIC3-mediated currents from rat dorsal root ganglion neurons with an IC50 of 230 nM. | |||||||||||||||||||||
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