63661-61-0
Chemical Structure
Budipine hydrochloride
- CAS No.: 63661-61-0
- Formula:C21H28ClN
- Molecular Weight:329.91
IUPAC Name: 1-(tert-butyl)-4,4-diphenylpiperidine hydrochloride
InChIKey: USUUKNCFNKZGEY-UHFFFAOYSA-N
SMILES: CC(N1CCC(C2=CC=CC=C2)(C3=CC=CC=C3)CC1)(C)C.[H]Cl
Biological Activity: Budipine hydrochloride is an anti-parkinson agent. Budipine hydrochloride also is a substrate of P-glycoprotein (P-gp), is mediated the uptake into the brain by P-gp. Budipine hydrochloride also is N-methyl-d-aspartate (NMDA) antagonist, and has indirect dopaminergic effects through an improved dopamine release, the inhibition of monoamine oxidase type B (MAO-B). Budipine hydrochloride can be used for the research of CNS disorders include Parkinson disease[1].
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Budipine hydrochloride | Budipine hydrochloride is an anti-parkinson agent. Budipine hydrochloride also is a substrate of P-glycoprotein (P-gp), is mediated the uptake into the brain by P-gp. Budipine hydrochloride also is N-methyl-d-aspartate (NMDA) antagonist, and has indirect dopaminergic effects through an improved dopamine release, the inhibition of monoamine oxidase type B (MAO-B). Budipine hydrochloride can be used for the research of CNS disorders include Parkinson disease. | |||||||||||||||||||||
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