689297-68-5
Chemical Structure
KV2 channel inhibitor-1
- CAS No.: 689297-68-5
- Formula:C20H17ClN4OS
- Molecular Weight:396.89
IUPAC Name: 3-(3-chlorophenyl)-N-(2-(thiazol-4-yl)-1H-benzo[d]imidazol-6-yl)butanamide
InChIKey: MRQZOINSVKHDQS-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C2N=C(C3=CSC=N3)NC2=C1)CC(C)C4=CC=CC(Cl)=C4
Biological Activity: KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KV2 channel inhibitor-1 | 98.73% | KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels. | ||||||||||||||||||||
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Keywords
