69297-40-1
Chemical Structure
3-O-cis-p-Coumaroyl maslinic acid
- CAS No.: 69297-40-1
- Formula:C39H54O6
- Molecular Weight:618.84
IUPAC Name: (4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-11-hydroxy-10-(((Z)-3-(4-hydroxyphenyl)acryloyl)oxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylic acid
InChIKey: KWLOAKAXMOYBRK-JHXZZHGESA-N
SMILES: O[C@H]1[C@@H](C(C)([C@@]([H])([C@@]2(C1)C)CC[C@@]3([C@@]2(CC=C4[C@]3(CC[C@@]5([C@]4(CC(C)(CC5)C)[H])C(O)=O)C)[H])C)C)OC(/C=C\C6=CC=C(C=C6)O)=O
Biological Activity: 3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts[1][2].
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3-O-cis-p-Coumaroyl maslinic acid | 3-O-cis-p-Coumaroyl maslinic acid (compound 16) is a natural compound isolated from the ethyl acetate extract of leaves of Miconia albicans.3-O-cis-p-Coumaroyl maslinic acid can inhibit PTP1B, with the IC50 of 0.46 μM, and shows antimicrobial activity on Gram-positive bacteria and yeasts. | |||||||||||||||||||||
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References
- [1]. de Cássia Lemos Lima R, et al. High-Resolution PTP1B Inhibition Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of PTP1B Inhibitors from Miconia albicans. Molecules. 2018;23(7):1755. [Content Brief]
- [2]. Braca A, et al. Antimicrobial triterpenoids from Licania heteromorpha. Planta Med. 2000;66(8):768-769. [Content Brief]
