694466-00-7
Chemical Structure
hCAI/II-IN-6
- CAS No.: 694466-00-7
- Formula:C19H24N4O3S
- Molecular Weight:388.48
IUPAC Name: 2-(4-benzylpiperazin-1-yl)-N-(4-sulfamoylphenyl)acetamide
InChIKey: VMBFFHZLNCWIEC-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(S(=O)(N)=O)C=C1)CN2CCN(CC3=CC=CC=C3)CC2
Biological Activity: hCAI/II-IN-6 is an orally active human carbonic anhydrase (CA) inhibitor. hCAI/II-IN-6 selectively inhibits hCA II and hCA VII isoforms with Ki values of 220, 4.9, 6.5 and ＞50000 nM for hCA I, hCA II , hCA VII and hCA XII respectively. hCAI/II-IN-6 shows anticonvulsant activity and anti maximal electroshock (MES) activity in vivo. hCAI/II-IN-6 can be used for the research of epilepsy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
hCAI/II-IN-6 | 98.0% | hCAI/II-IN-6 is an orally active human carbonic anhydrase (CA) inhibitor. hCAI/II-IN-6 selectively inhibits hCA II and hCA VII isoforms with Ki values of 220, 4.9, 6.5 and ＞50000 nM for hCA I, hCA II , hCA VII and hCA XII respectively. hCAI/II-IN-6 shows anticonvulsant activity and anti maximal electroshock (MES) activity in vivo. hCAI/II-IN-6 can be used for the research of epilepsy. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
