701947-53-7
701947-53-7
Chemical Structure
DM-PIT-1
Synonym(s): 3,5-Dimethyl PIT-1
- CAS No.: 701947-53-7
- Formula:C16H15N3O4S
- Molecular Weight:345.37
IUPAC Name: N-((2-hydroxy-5-nitrophenyl)carbamothioyl)-3,5-dimethylbenzamide
InChIKey: CGWBCAQMXJFWBU-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C)=CC(C)=C1)NC(NC2=C(C=CC([N+]([O-])=O)=C2)O)=S
Biological Activity: DM-PIT-1 is a PIP3/PH (phosphatidylinositol-3,4,5-triphosphate/Pleckstrin) interaction inhibitor. DM-PIT-1 decreases he expression of P-Akt, P-GSK-3-β, P-p70S6K, P-S6, P-4E-BP1. DM-PIT-1 induces apoptosis and shows anticancer activity. DM-PIT-1 has the potential for the research of ovarian cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DM-PIT-1 | 99.9% | DM-PIT-1 is a PIP3/PH (phosphatidylinositol-3,4,5-triphosphate/Pleckstrin) interaction inhibitor. DM-PIT-1 decreases he expression of P-Akt, P-GSK-3-β, P-p70S6K, P-S6, P-4E-BP1. DM-PIT-1 induces apoptosis and shows anticancer activity. DM-PIT-1 has the potential for the research of ovarian cancer. | ||||||||||||||||||||
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