70222-95-6
Chemical Structure
N,N-Dimethyldoxorubicin
- CAS No.: 70222-95-6
- Formula:C29H33NO11
- Molecular Weight:571.57
IUPAC Name: (8S,10S)-10-(((2R,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
InChIKey: DJEFXYVVRUAFEB-KYZOVJJKSA-N
SMILES: OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N(C)C)=C1C[C@](O)(C4)C(CO)=O
Biological Activity: N,N-Dimethyldoxorubicin is an analog of Doxorubicin (HY-15142A). N,N-Dimethyldoxorubicin induces chromatin damage via histone eviction, while barely inducing DNA double-strand breaks. N,N-Dimethyldoxorubicin exhibits cytotoxicity against a variety of tumor cells. N,N-Dimethyldoxorubicin can be used in research related to multiple types of cancer[1].
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N,N-Dimethyldoxorubicin | N,N-Dimethyldoxorubicin is an analog of Doxorubicin (HY-15142A). N,N-Dimethyldoxorubicin induces chromatin damage via histone eviction, while barely inducing DNA double-strand breaks. N,N-Dimethyldoxorubicin exhibits cytotoxicity against a variety of tumor cells. N,N-Dimethyldoxorubicin can be used in research related to multiple types of cancer. | |||||||||||||||||||||
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