70648-26-9
70648-26-9
Chemical Structure
1,2,3,4,7,8-Hexachlorodibenzofuran
Synonym(s): 1,2,3,4,7,8-HxCDF
- CAS No.: 70648-26-9
- Formula:C12H2Cl6O
- Molecular Weight:374.86
InChIKey: LVYBAQIVPKCOEE-UHFFFAOYSA-N
SMILES: ClC1=CC2=C(C=C1Cl)C3=C(Cl)C(Cl)=C(Cl)C(Cl)=C3O2
Biological Activity: 1,2,3,4,7,8-Hexachlorodibenzofuran (1,2,3,4,7,8-HxCDF) promotes the gene expressions of CYP1A1, CYP1B1, and aryl hydrocarbon receptor repressor (AhRR) in human peripheral blood lymphocytes (PBLs). 1,2,3,4,7,8-Hexachlorodibenzofuran activates the ethoxyresorufin-Odeethylase, achieves 20% of the maximum response caused by TCDD with a BMR20TCDD of 0.115-0.143 nM[1].
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1,2,3,4,7,8-Hexachlorodibenzofuran | 1,2,3,4,7,8-Hexachlorodibenzofuran (1,2,3,4,7,8-HxCDF) promotes the gene expressions of CYP1A1, CYP1B1, and aryl hydrocarbon receptor repressor (AhRR) in human peripheral blood lymphocytes (PBLs). 1,2,3,4,7,8-Hexachlorodibenzofuran activates the ethoxyresorufin-Odeethylase, achieves 20% of the maximum response caused by TCDD with a BMR20TCDD of 0.115-0.143 nM. | |||||||||||||||||||||
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1,2,3,4,7,8-Hexachloro-dibenzofuran-13C12 | 1, 2, 3, 4, 7, 8- Hexachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,7,8-Hexachlorodibenzofuran. | |||||||||||||||||||||
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References
