70762-66-2
70762-66-2
Chemical Structure
Chinifur
Synonym(s): Quinifuryl
- CAS No.: 70762-66-2
- Formula:C25H30N4O4
- Molecular Weight:450.53
IUPAC Name: (E)-N-(5-(diethylamino)pentan-2-yl)-2-(2-(5-nitrofuran-2-yl)vinyl)quinoline-4-carboxamide
InChIKey: MTHCJDYSIZMKAC-OUKQBFOZSA-N
SMILES: O=C(C1=C2C=CC=CC2=NC(/C=C/C3=CC=C([N+]([O-])=O)O3)=C1)NC(CCCN(CC)CC)C
Biological Activity: Chinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chinifur | 98.02% | Chinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM). | ||||||||||||||||||||
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References
- [1]. Iribarne F, et al. Interaction energies of nitrofurans with trypanothione reductase and glutathione reductase studied by molecular docking[J]. Journal of Molecular Structure: THEOCHEM, 2007, 818(1-3): 7-22.
- [2]. Cenas N, et al. Chinifur, a selective inhibitor and" subversive substrate" for Trypanosoma congolense trypanothione reductase[J]. Biochemical and biophysical research communications, 1994, 204(1): 224-229. [Content Brief]
Keywords
