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  4. Chinifur

Chinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM).

For research use only. We do not sell to patients.

Chinifur

Chinifur Chemical Structure

CAS No. : 70762-66-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
250 mg Get quote
1 g Get quote
5 g Get quote
10 g   Get quote  
50 g   Get quote  

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Chinifur Related Antibodies

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

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Description

Chinifur (Quinifuryl), a Nitrofuran derivative, is a selective inhibitor of trypanothione reductase and also a radical-generating substrate for trypanothione reductase (Ki = 4.5 μM)[1][2].

IC50 & Target

Ki: 4.5 μM (trypanothione reductase)[1].
Molecular Weight

450.53

Formula

C25H30N4O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=C2C=CC=CC2=NC(/C=C/C3=CC=C([N+]([O-])=O)O3)=C1)NC(CCCN(CC)CC)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (27.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2196 mL 11.0980 mL 22.1961 mL
5 mM 0.4439 mL 2.2196 mL 4.4392 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2196 mL 11.0980 mL 22.1961 mL 55.4902 mL
5 mM 0.4439 mL 2.2196 mL 4.4392 mL 11.0980 mL
10 mM 0.2220 mL 1.1098 mL 2.2196 mL 5.5490 mL
15 mM 0.1480 mL 0.7399 mL 1.4797 mL 3.6993 mL
20 mM 0.1110 mL 0.5549 mL 1.1098 mL 2.7745 mL
25 mM 0.0888 mL 0.4439 mL 0.8878 mL 2.2196 mL
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Chinifur Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chinifur70762-66-2QuinifurylParasiteNitrofuransTrypanothione reductaseChagas’ diseaseInhibitorinhibitorinhibit

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