747-90-0
Chemical Structure
Cholesta-3,5-diene
Synonym(s): delta-3,5-Cholestadiene
- CAS. Nr.: 747-90-0
- Formula:C27H44
- Molecular Weight:368.64
IUPAC Name: (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene
InChIKey: RLHIRZFWJBOHHD-HKQCOZBKSA-N
SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C=CCC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: Cholesta-3,5-diene is an inflammatory modulator that targets immune cells such as neutrophils and accelerates wound healing by promoting neutrophil chemotaxis and fibroblast migration. Cholesta-3,5-diene enhances immune cell recruitment and extracellular matrix deposition by activating chemokine receptor-mediated signaling pathways such as PI3K/Akt. Cholesta-3,5-diene can be applied topically to wound repair and has potential therapeutic value in chronic ulcers or skin lesions[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Cholesta-3,5-diene | 99.54% | Cholesta-3,5-diene is an inflammatory modulator that targets immune cells such as neutrophils and accelerates wound healing by promoting neutrophil chemotaxis and fibroblast migration. Cholesta-3,5-diene enhances immune cell recruitment and extracellular matrix deposition by activating chemokine receptor-mediated signaling pathways such as PI3K/Akt. Cholesta-3,5-diene can be applied topically to wound repair and has potential therapeutic value in chronic ulcers or skin lesions. | ||||||||||||||||||||
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- [1]. Al-Hassan JM, et al. Potential Mechanism of Dermal Wound Treatment With Preparations From the Skin Gel of Arabian Gulf Catfish: A Unique Furan Fatty Acid (F6) and Cholesta-3,5-Diene (S5) Recruit Neutrophils and Fibroblasts to Promote Wound Healing. Front Pharmacol. 2020 Jun 18;11:899. [Content Brief]
- [2]. Derewiaka D. Formation of cholesterol oxidation products, cholesterol dimers and cholestadienes after thermal processing of cholesterol standards and butter[J]. European Journal of Lipid Science and Technology, 2019, 121(9): 1800373.
Keywords
