761436-62-8
761436-62-8
Chemical Structure
NVP-TAC544
- CAS No.: 761436-62-8
- Formula:C22H25BrN6O4S
- Molecular Weight:549.44
InChIKey: YSDPMNWDZMLLLK-UHFFFAOYSA-N
SMILES: O=S(NC)(C1=C(NC2=NC(NC3=CC=C(N4CCOCC4)C=C3OC)=NC=C2Br)C=CC=C1)=O
Biological Activity: NVP-TAC544 is a focal adhesion kinase (FAK) inhibitor. NVP-TAC544 inhibits angiogenesis. NVP-TAC544 can be used for the research of melanoma (primary or metastatic)[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
NVP-TAC544 | NVP-TAC544 is a focal adhesion kinase (FAK) inhibitor. NVP-TAC544 inhibits angiogenesis. NVP-TAC544 can be used for the research of melanoma (primary or metastatic). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Weis SM, et al. Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK. J Cell Biol. 2008;181(1):43-50. [Content Brief]
- [2]. Chuang HH, et al. FAK in Cancer: From Mechanisms to Therapeutic Strategies. Int J Mol Sci. 2022;23(3):1726. Published 2022 Feb 2. [Content Brief]
Keywords
