77599-17-8
Chemical Structure
Panomifene
Synonym(s): EGIS 5650; GYKI-13504
- CAS No.: 77599-17-8
- Formula:C25H24F3NO2
- Molecular Weight:427.46
IUPAC Name: (E)-2-((2-(4-(3,3,3-trifluoro-1,2-diphenylprop-1-en-1-yl)phenoxy)ethyl)amino)ethan-1-ol
InChIKey: MHXVDXXARZCVRK-WCWDXBQESA-N
SMILES: FC(F)(/C(C1=CC=CC=C1)=C(C2=CC=C(C=C2)OCCNCCO)\C3=CC=CC=C3)F
Biological Activity: Panomifene (EGIS 5650) is a tamoxifen (HY-13757A) analog with an antiestrogenic activity. Panomifene can be used in the research of breast cancer[1][2].
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Panomifene | Panomifene (EGIS 5650) is a tamoxifen (HY-13757A) analog with an antiestrogenic activity. Panomifene can be used in the research of breast cancer. | |||||||||||||||||||||
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- [1]. V Erdélyi-Tóth, et al. Determination of panomifene in human plasma by high-performance liquid chromatography. J Chromatogr A. 1994 May 13;668(2):419-25. [Content Brief]
- [2]. Tobias Michael Milzarek, et al. Synthesis of Trifluoromethylated Alkenes: Hypervalent Iodine Meets High-Valent Copper. Angew Chem Int Ed Engl. 2023 Aug 14;62(33):e202306128. [Content Brief]
Keywords