78499-27-1
78499-27-1
Chemical Structure
Bermoprofen
Synonym(s): AD-1590
- CAS. Nr.: 78499-27-1
- Formula:C18H16O4
- Molecular Weight:296.32
IUPAC Name: 2-(8-methyl-11-oxo-10,11-dihydrodibenzo[b,f]oxepin-2-yl)propanoic acid
InChIKey: REHLODZXMGOGQP-UHFFFAOYSA-N
SMILES: O=C(O)C(C)C1=CC=C(C2=C1)OC3=CC=C(C)C=C3CC2=O
Biological Activity: Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits[1][2].
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Bermoprofen | Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory agent. Bermoprofen has potent antipyretic activities with a short biological half-life. Bermoprofen is a potent antagonist of LPS-induced fever in rabbits. | |||||||||||||||||||||
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References
- [1]. Mori M, et al. Prolongation of antipyretic action and reduction of gastric ulcerogenicity in the rat by controlled-release granules of bermoprofen, a new nonsteroidal anti-inflammatory drug. J Pharm Sci. 1991 Sep;80(9):876-80. [Content Brief]
- [2]. Nakamura H, et al. AD-1590, a potent antagonist of lipopolysaccharide-induced fever in rabbits. J Pharm Pharmacol. 1984 Mar;36(3):182-6. [Content Brief]
Keywords
