79974-70-2
Chemical Structure
N2-iBu-2’,3’-bis-O-TBDMS guanosine
- CAS 番号: 79974-70-2
- Formula:C26H47N5O6Si2
- Molecular Weight:581.85
IUPAC Name: N-(9-((2R,3R,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
InChIKey: VZMILHMVPGBTBQ-DYVMYPEFSA-N
SMILES: OC[C@H]1O[C@@H](N(C=N2)C3=C2C(NC(NC(C(C)C)=O)=N3)=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C
Biological Activity: N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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N2-iBu-2’,3’-bis-O-TBDMS guanosine | N2-iBu-2’,3’-bis-O-TBDMS guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords
