848142-62-1
Chemical Structure
Indazole-Cl
Synonym(s): Ind-Cl
- CAS No.: 848142-62-1
- Formula:C13H9ClN2O2
- Molecular Weight:260.68
IUPAC Name: 3-chloro-2-(4-hydroxyphenyl)-2H-indazol-5-ol
InChIKey: ZNHQDSBJVFFIAK-UHFFFAOYSA-N
SMILES: OC1=CC2=C(Cl)N(C3=CC=C(O)C=C3)N=C2C=C1
Biological Activity: Indazole-Cl (Ind-Cl) is an Estrogen receptor (ER)-β-specific agonist with inflammatory effect. Indazole-Cl inhibits cyclooxygenase-2 exression reduction induced by hypoxia. And Indazole-Cl inhibits ROS production. Indazole-Cl also inhibits cell migration and invasion by hypoxia increased by hypoxia. Indazole-Cl is potent inhibitor of hypoxia-induced inflammation in vascular smooth muscle cells (VSMCs)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Indazole-Cl | 98.19% | Indazole-Cl (Ind-Cl) is an Estrogen receptor (ER)-β-specific agonist with inflammatory effect. Indazole-Cl inhibits cyclooxygenase-2 exression reduction induced by hypoxia. And Indazole-Cl inhibits ROS production. Indazole-Cl also inhibits cell migration and invasion by hypoxia increased by hypoxia. Indazole-Cl is potent inhibitor of hypoxia-induced inflammation in vascular smooth muscle cells (VSMCs). | ||||||||||||||||||||
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