848144-15-0
Chemical Structure
ITX5061 free base
- CAS No.: 848144-15-0
- Formula:C30H37N3O7S
- Molecular Weight:583.70
IUPAC Name: N-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)-2-(4-(2-morpholinoethoxy)naphthalen-1-yl)-2-oxoacetamide
InChIKey: UUROSJLZNDSXRF-UHFFFAOYSA-N
SMILES: O=C(NC=1C=C(C=C(NS(=O)(=O)C)C1OC)C(C)(C)C)C(=O)C2=CC=C(OCCN3CCOCC3)C=4C=CC=CC24
Biological Activity: ITX5061 free base is an orally active type II non-competitive p38 MAPK inhibitor. ITX5061 free base increases HDL-C levels by inhibiting SR-BI activity. ITX5061 free base also moderately elevates ApoA-I levels. ITX5061 free base reduces early atherosclerotic lesions in the aortic arch of mice fed an atherogenic diet. ITX5061 free base can be used in the research of atherosclerosis[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ITX5061 free base | ITX5061 free base is an orally active type II non-competitive p38 MAPK inhibitor. ITX5061 free base increases HDL-C levels by inhibiting SR-BI activity. ITX5061 free base also moderately elevates ApoA-I levels. ITX5061 free base reduces early atherosclerotic lesions in the aortic arch of mice fed an atherogenic diet. ITX5061 free base can be used in the research of atherosclerosis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
