864295-20-5
Chemical Structure
BI-11634 free base
- CAS No.: 864295-20-5
- Formula:C22H23ClN4O4
- Molecular Weight:442.90
IUPAC Name: (R)-N-(1-(5-chloro-1H-benzo[d]imidazol-2-yl)-2-methoxyethyl)-3-methyl-4-(3-oxomorpholino)benzamide
InChIKey: XSHZWZJZXDICAQ-SFHVURJKSA-N
SMILES: [C@H](NC(=O)C1=CC(C)=C(C=C1)N2C(=O)COCC2)(COC)C=3NC=4C(N3)=CC(Cl)=CC4
Biological Activity: BI-11634 free base is an orally active factor Xa inhibitor and a CYP3A4 substrate. The apparent Km values for BI-11634 free base metabolism are 23 μM in human liver microsomes (HLMs) and 7.6 μM with recombinant CYP3A4. BI-11634 free base can be used for thromboembolic disease and CYP3A4-mediated drug metabolism research[1].
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BI-11634 free base | BI-11634 free base is an orally active factor Xa inhibitor and a CYP3A4 substrate. The apparent Km values for BI-11634 free base metabolism are 23 μM in human liver microsomes (HLMs) and 7.6 μM with recombinant CYP3A4. BI-11634 free base can be used for thromboembolic disease and CYP3A4-mediated drug metabolism research. | |||||||||||||||||||||
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Keywords
