890297-34-4
Chemical Structure
Tyrosinase-IN-52
- CAS No.: 890297-34-4
- Formula:C19H21FN4O3
- Molecular Weight:372.39
InChIKey: HEKLEZHYUZYOEW-UHFFFAOYSA-N
SMILES: FC(C=C1)=CC=C1CN2CCN(CC(NC3=CC=C([N+]([O-])=O)C=C3)=O)CC2
Biological Activity: Tyrosinase-IN-52 is a synthetic heterocyclic derivative of 4-(4-fluorobenzyl) piperazine-acetanilide that possesses tyrosinase inhibitory activity (mushroom IC50 = 85.24 μM). Tyrosinase-IN-52 modulates melanogenesis through a biphasic effect, thereby regulating melanin content, and weakly scavenges DPPH radicals. Tyrosinase-IN-52 exhibits low cytotoxicity against mouse fibroblast 3T3 cells. Tyrosinase-IN-52 can be used for pigmentation-related research[1].
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Tyrosinase-IN-52 | Tyrosinase-IN-52 is a synthetic heterocyclic derivative of 4-(4-fluorobenzyl) piperazine-acetanilide that possesses tyrosinase inhibitory activity (mushroom IC50 = 85.24 μM). Tyrosinase-IN-52 modulates melanogenesis through a biphasic effect, thereby regulating melanin content, and weakly scavenges DPPH radicals. Tyrosinase-IN-52 exhibits low cytotoxicity against mouse fibroblast 3T3 cells. Tyrosinase-IN-52 can be used for pigmentation-related research. | |||||||||||||||||||||
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