891075-67-5
891075-67-5
Chemical Structure
AKR1C3-IN-12
- CAS No.: 891075-67-5
- Formula:C17H14N2O3
- Molecular Weight:294.30
InChIKey: SKZQOFVKMNLPBF-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(OC1=N)C(O)=CC=C2)NC3=CC=C(C)C=C3
Biological Activity: AKR1C3-IN-12 (compound 2j) is an aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 27 nM. AKR1C3-IN-12 enhances the efficacy of Gemcitabine and Cisplatin in bladder cancer[1].
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AKR1C3-IN-12 | AKR1C3-IN-12 (compound 2j) is an aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 27 nM. AKR1C3-IN-12 enhances the efficacy of Gemcitabine and Cisplatin in bladder cancer. | |||||||||||||||||||||
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References
Keywords
