89875-86-5
89875-86-5
Chemical Structure
Tiflucarbine
Synonym(s): BAY-P 4495
- CAS No.: 89875-86-5
- Formula:C16H17FN2S
- Molecular Weight:288.38
IUPAC Name: 9-ethyl-4-fluoro-1-methyl-7,8,9,10-tetrahydro-6H-pyrido[4,3-b]thieno[3,2-e]indole
InChIKey: BNKIWXODDDABSJ-UHFFFAOYSA-N
SMILES: FC1=C(SC=C2C)C2=C3C(CN(CC4)CC)=C4NC3=C1
Biological Activity: Tiflucarbine (BAY-P 4495) is a tetrahydrothieno-7-carboline derivative. Tiflucarbine is a potent antidepressant agent that binds at central serotonin (5-HT) binding sites. Tiflucarbine is a nonselective 5-HT (5-HT1 and 5-HT2) agonist[1][2].
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Tiflucarbine | Tiflucarbine (BAY-P 4495) is a tetrahydrothieno-7-carboline derivative. Tiflucarbine is a potent antidepressant agent that binds at central serotonin (5-HT) binding sites. Tiflucarbine is a nonselective 5-HT (5-HT1 and 5-HT2) agonist. | |||||||||||||||||||||
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References
- [1]. Schmidt BH, et al. Evidence for a specific recognition site for tiflucarbine on calmodulin. Eur J Pharmacol. 1990 Dec 15;189(6):411-8. [Content Brief]
- [2]. Glennon RA, et al. Stimulus properties of tiflucarbine: a novel antidepressant agent. Pharmacol Biochem Behav. 1990 Dec;37(4):769-71. [Content Brief]
Keywords
