9025-26-7
9025-26-7
Chemical Structure
Cathepsin D
Synonym(s): CTSD
- CAS No.: 9025-26-7
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Cathepsin D]
Biological Activity: Cathepsin D (CTSD) is a lysosomal aspartic protease encoded by the CTSD gene. Cathepsin D regulates lysosomal protease activity. Loss of Cathepsin D leads to lysosomal dysfunction and the accumulation of various cellular proteins associated with neurodegenerative diseases. Cathepsin D is involved in breast cancer metastasis. Cathepsin D can be used in research on diseases such as breast cancer and stroke[1][2].
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Cathepsin D | Cathepsin D (CTSD) is a lysosomal aspartic protease encoded by the CTSD gene. Cathepsin D regulates lysosomal protease activity. Loss of Cathepsin D leads to lysosomal dysfunction and the accumulation of various cellular proteins associated with neurodegenerative diseases. Cathepsin D is involved in breast cancer metastasis. Cathepsin D can be used in research on diseases such as breast cancer and stroke. | |||||||||||||||||||||
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References
- [1]. Hossain MI, et al. Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective. Autophagy. 2021 Jun;17(6):1330-1348. [Content Brief]
- [2]. Rochefort H, et al. Cathepsin D: a protease involved in breast cancer metastasis. Cancer Metastasis Rev. 1990 Dec;9(4):321-31. [Content Brief]
Keywords
