934655-87-5
934655-87-5
Chemical Structure
ODN M362
- CAS. Nr.: 934655-87-5
- Formula:N/A
- Molecular Weight:8049.50
SMILES: [DNA, d(P-thio)(T-C-G-T-C-G-T-C-G-T-T-C-G-A-A-C-G-A-C-G-T-T-G-A-T)]
Biological Activity: ODN M362, a class C oligodeoxynucleotide, is a TLR-9 agonist and can be used as a vaccine adjuvant. ODN M362 induces cancer cell apoptosis[1][2].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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ODN M362 | 96.01% | ODN M362, a class C oligodeoxynucleotide, is a TLR-9 agonist and can be used as a vaccine adjuvant. ODN M362 induces cancer cell apoptosis. | ||||||||||||||||||||
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References
- [1]. Babaer D, et al. Oligodeoxynucleotides ODN 2006 and M362 Exert Potent Adjuvant Effect through TLR-9/-6 Synergy to Exaggerate Mammaglobin-A Peptide Specific Cytotoxic CD8+T Lymphocyte Responses against Breast Cancer Cells. Cancers (Basel). 2019 May 14;11(5):672. [Content Brief]
- [2]. Zhang Y, et al. Phosphorothioate-modified CpG oligodeoxynucleotide (CpG ODN) induces apoptosis of human hepatocellular carcinoma cells independent of TLR9. Cancer Immunol Immunother. 2014 Apr;63(4):357-67. [Content Brief]
