98644-22-5
98644-22-5
Chemical Structure
CM 57373
- CAS No.: 98644-22-5
- Formula:C10H14BrN3
- Molecular Weight:256.15
IUPAC Name: 1-(6-bromopyridin-2-yl)piperidin-4-amine
InChIKey: QGIXHPDIJWYJAV-UHFFFAOYSA-N
SMILES: BrC=1N=C(C=CC1)N2CCC(N)CC2
Biological Activity: CM 57373 is an orally active anorectic agent. CM 57373 releases serotonin and inhibits serotonin reuptake in rat brain synaptosomes. CM 57373 reduces food intake, decreases body weight and alleviates experimentally induced hyperphagia. CM 57373 can be used in obesity research[1][2].
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CM 57373 | CM 57373 is an orally active anorectic agent. CM 57373 releases serotonin and inhibits serotonin reuptake in rat brain synaptosomes. CM 57373 reduces food intake, decreases body weight and alleviates experimentally induced hyperphagia. CM 57373 can be used in obesity research. | |||||||||||||||||||||
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References
- [1]. Fuller RW, et al. Neurochemical effects of CM 57227 and CM 57373, two anorectic agents, on brain serotonin neurons in rats. Neurochemistry international. 1990;16(3):309-12. [Content Brief]
- [2]. Miranda GF, et al. Reduction of normal food intake in rats and dogs and inhibition of experimentally induced hyperphagia in rats by CM 57373 and fenfluramine. European journal of pharmacology. 1988 May 20;150(1-2):155-61. [Content Brief]
Keywords
