99420-15-2
99420-15-2
Chemical Structure
BTZO-1
- CAS No.: 99420-15-2
- Formula:C13H8N2OS
- Molecular Weight:240.28
IUPAC Name: 2-(pyridin-2-yl)-4H-benzo[e][1,3]thiazin-4-one
InChIKey: GBAKVEWPYUIGHN-UHFFFAOYSA-N
SMILES: O=C1N=C(C2=NC=CC=C2)SC3=CC=CC=C13
Biological Activity: BTZO-1, a chemical probe, binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BTZO-1 | 99.32% | BTZO-1, a chemical probe, binds to Macrophage migration inhibitory factor (MIF) with a Kd value of 68.6 nM, and its binding requires the N-terminal Pro1. BTZO-1 can activate antioxidant response element (ARE)-mediated gene expression and suppress oxidative stress-induced cardiomyocyte apoptosis in vitro. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
