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Cat. No.: HY-181852

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CBP/p300 ligand 10

CBP/p300 ligand 10 (Compound 3-E) is a CBP/p300 degrader. CBP/p300 ligand 10 also serves as a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) and can be used to synthesize the PROTAC CBP/p300 Degrader-2 (HY-181261).

For research use only. We do not sell to patients.

CAS No.: 3098454-51-1
Formula: C₂₉H₃₀F₂N₄O₂
Molecular Weight:504.57

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CBP/p300 ligand 10 Chemical Structure

CAS No.: 3098454-51-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Histone Acetyltransferase Isoforms :

Chemical Information

CAS No. 3098454-51-1
Molecular Weight 504.57
Formula C₂₉H₃₀F₂N₄O₂
SMILES

CC(C(N(C1=C2)C)=O)=CC1=C(N3CCCC(C=C4C5=CNN=C5)=C3C=C4C(F)F)C=C2C6CCOCC6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chandrasekhar ABBINENI, et al. Substituted heterocyclic compounds and their derivatives as cbp and/or p300 degraders. WO2025202979A1. 2025-10-02

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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