AMRI-59
AMRI-59 is a potent inhibitor of PrxI used for parasitic infections. AMRI-59 can increase cellular ROS, leading to activation of signaling pathways mediated by mitochondria and apoptosis signal-regulated kinase 1, thereby leading to apoptosis in A549 human lung adenocarcinoma. AMRI-59 exhibits significant antitumor activity without apparent acute toxicity.
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- CAS. Nr.: 923515-92-8
- Formel: C25H27N3O2
- Molecular Weight:401.50
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
PrxI[1]
Chemical Information
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CAS. Nr. 923515-92-8
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Molecular Weight 401.50
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Formel C25H27N3O2
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SMILES
O=C(N1CCC(CC2=CC=C(N3C=CC=C3)C=C2)CC1)NC4=CC=CC(C(C)=O)=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AMRI-59 Related Classifications
HY-111125 Related Classifications
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