Toborinone
Toborinone is an inotropic agent. Toborinone increases cAMP and intracellular calcium levels through inhibiting PDE. Toborinone inhibits thrombin-induced platelet aggregation with an IC50 of 9.7 μM.
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- CAS. Nr.: 143343-83-3
- Formel: C21H24N2O5
- Molecular Weight:384.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 143343-83-3
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Molecular Weight 384.43
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Formel C21H24N2O5
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SMILES
COC1=C(C=CC(CNCC(COC2=CC=C3C(C=CC(N3)=O)=C2)O)=C1)OC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. MacGowan G. A. (2000). Clinical overview of the novel inotropic agent toborinone. Expert opinion on investigational drugs, 9(5), 1109-1117. [Content Brief]
[2]. Kageyama, K., et al., (2004). Toborinone and olprinone, phosphodiesterase III inhibitors, inhibit human platelet aggregation due to the inhibition of both calcium release from intracellular stores and calcium entry. Journal of anesthesia, 18(2), 107-112. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Toborinone Related Classifications
HY-165436 Related Classifications
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