2 Results for "

p38 MAPK-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "p38 MAPK-IN-8" in MCE Product Catalog:

Cat. No.: HY-175431
CAS No.: 208182-49-4
Target:  

p38 MAPK

Research Areas:  

Inflammation/Immunology Cancer

p38 MAPK-IN-8 (Compound 8) is an orally active, potent and selective p38 mitogen-activated protein kinase (p38 MAPK) inhibitor. p38 MAPK-IN-8 is promising for research of inflammatory responses, autoimmune diseases, and cancer .
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Cat. No.: HY-172100
Research Areas:  

Cancer

p38-α MAPK-IN-8 (Compound 13) is a lipophilic cationic derivative. p38-α MAPK-IN-8 is cytotoxic to various tumor cells, and can induce cell cycle arrest, apoptosis, increase reactive oxygen species (ROS) production, and induce mitochondrial membrane potential depolarization. The antitumor activity of p38-α MAPK-IN-8 may be related to p38α MAPK pathway, which can be used in the study of cancer .
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