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Cat. No.: HY-184877

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CDK4-IN-8

CDK4-IN-8 is a selective CDK4 inhibitor with no activity against CDK6, and it inhibits the proliferation of breast cancer cells. CDK4-IN-8 can be used in breast cancer-related research.

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CAS No.: 2764984-10-1
Formule: C₂₇H₃₁FN₆OS
Masse moléculaire:506.64

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK4-IN-8 Chemical Structure

CAS No.: 2764984-10-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

CDK4-IN-8 is a selective CDK4 inhibitor with no activity against CDK6, and it inhibits the proliferation of breast cancer cells. CDK4-IN-8 can be used in breast cancer-related research^[1].

IC₅₀ & Target^[1]

CDK4

Voir tous les produits spécifiques à Isoform CDK :

In Vitro

CDK4-IN-8 (example 98) exhibits potent inhibitory activity against CDK4_D1 kinase, shows moderate antiproliferative activity against MCF7 adenocarcinoma cells, and has no obvious inhibitory activity against CDK6_D1 kinase^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2764984-10-1
Masse moléculaire 506.64
Formule C₂₇H₃₁FN₆OS
SMILES

O=C1C2=C(SC(C=3N=C(N=CC3F)NC4=NC=C(C=C4)C5CCN(C)CC5)=C2C)C(=CN1C)C(C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Buesking A W, et al. Cdk inhibitors and their use as pharmaceuticals. WO2022061273A1. WIPO. 2022.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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CDK4-IN-8

Voir tous les produits spécifiques à Isoform CDK

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CDK4-IN-8 Related Classifications

HY-184877 Related Classifications