PF-06842874
PF-06842874 is a CDK4/Cyclin D1 and CDK6/Cyclin D3 inhibitor (Ki values are 62 and 130 nM, respectively). PF-06842874 can be used in the research of pulmonary arterial hypertension and cancer.
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- CAS No.: 2516247-98-4
- Formule: C21H27N3O4
- Masse moléculaire:385.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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CDK4/cyclinD1 62 nM (Ki) |
cdk6/cyclin D3 130 nM (Ki) |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2516247-98-4
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Masse moléculaire 385.46
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Formule C21H27N3O4
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SMILES
O=C1N(C2CCCC2)C3=CC(N[C@H]4[C@@H](COCC4)O)=NC=C3C(C)=C1C(C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PF-06842874 Related Classifications
HY-172234 Related Classifications
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