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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
M3-antagonist,
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "M3-antagonist," in MCE Product Catalog:
Cat. No.: HY-101586
CAS No.: 120241-31-8
Synonyms: Lu 25-109
Target:
Domaines de recherche:
Alvameline (Lu25-109) is a partial M1 agonist and M2/M3 antagonist.
Cat. No.: HY-120802
CAS No.: 1435519-06-4
Synonyms: AZD-8871; LAS191351
Target:
Domaines de recherche:
Navafenterol (AZD-8871) is an inhaled dual-acting, potent, selective, and long-lasting M3-antagonist/β2-agonist (MABA) with long-lasting effects and favorable safety profile. The pIC50 is 9.5 for human M3 receptor, and the pEC50 is 9.5 for β2-adrenoceptor. Navafenterol can be used for the research of chronic obstructive pulmonary disease (COPD). Bronchoprotective and antisialagogue effects. Favorable cardiovascular profile .
Cat. No.: HY-177309
CAS No.: 886490-58-0
Target:
Domaines de recherche:
Muscarinic M3 receptor antagonist-1 (Example 4) is a muscarinic acetylcholine receptor M3 antagonist. Muscarinic M3 receptor antagonist-1 can be used to study inflammatory and obstructive airway diseases .
Cat. No.: HY-107653
CAS No.: 257603-40-0
Target:
Domaines de recherche:
J 104129 fumarate is a selective and orally active muscarinic M3 antagonist with Ki values of 4.2 nM and 490 nM for M3 and M2, respectively. J 104129 fumarate antagonized ACh-induced bronchoconstriction. J 104129 fumarate has the potential for the research of obstructive airway disease .
Cat. No.: HY-113692
CAS No.: 1034916-72-7
AZD-9164 (bromide) is a long-acting muscarinic M3 antagonist. AZD-9164 (bromide) is promising for research of airways diseases, such as chronic obstructive pulmonary disease (COPD) or asthma .
Cat. No.: HY-123566
CAS No.: 754177-77-0
Synonyms: RO 3202904
Target:
Domaines de recherche:
PSD-506 (RO 3202904) is a muscarinic M2/M3 antagonist. PSD-506 has the potential to be used in studies of bladder overactivity and urinary incontinence .
Cat. No.: HY-169814
CAS No.: 221549-70-8
Target:
Domaines de recherche:
Lu 25-077 is a brain-penetrant and pharmacologically active N-demethyl metabolite of Lu 25-109 (HY-101586), a partial M1 agonist and M2/M3 antagonist. Lu 25-077 can be utilized in neurological research .
Cat. No.: HY-120802A
CAS No.: 1648550-37-1
Synonyms: AZD-8871 saccharinate; LAS191351 saccharinate
Target:
Domaines de recherche:
Navafenterol (AZD-8871) saccharinate is an inhaled dual-acting, potent, selective, and long-lasting M3-antagonist/β2-agonist (MABA) with long-lasting effects and favorable safety profile. The pIC50 is 9.5 for human M3 receptor, and the pEC50 is 9.5 for β2-adrenoceptor. Navafenterol saccharinate can be used for the research of chronic obstructive pulmonary disease (COPD). Bronchoprotective and antisialagogue effects. Favorable cardiovascular profile .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
