1. Anti-infection
  2. Fungal
  3. Cladobotric acid H

Cladobotric acid H is a polyketide antifungal agent found in the mycoparasitic fungus Hypomyces pseudocorticicola FKA-73. Cladobotric acid H inhibits growth of azole-sensitive and azole-resistant Candida auris, Aspergillus fumigatus, Aspergillus udagawae, Aspergillus felis, and Aspergillus lentulus. Cladobotric acid H can be used for the research of aspergillosis, candidiasis.

For research use only. We do not sell to patients.

Cladobotric acid H

Cladobotric acid H Chemical Structure

CAS No. : 2900278-39-7

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Description

Cladobotric acid H is a polyketide antifungal agent found in the mycoparasitic fungus Hypomyces pseudocorticicola FKA-73. Cladobotric acid H inhibits growth of azole-sensitive and azole-resistant Candida auris, Aspergillus fumigatus, Aspergillus udagawae, Aspergillus felis, and Aspergillus lentulus. Cladobotric acid H can be used for the research of aspergillosis, candidiasis[1].

In Vitro

Cladobotric acid H (compound 123) (16-64 μg/mL) inhibits the growth of A. fumigatus IFM 61493, A. fumigatus IFM 62104, and C. auris IFM 65061 with an MIC of 32 μg/mL, A. udagawae IFM 62100, A. felis IFM 62093, and A. lentulus IFM 62073 with an MIC of 64 μg/mL, and C. auris IFM 64524 and C. auris IFM 65059 with an MIC of 16 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

440.58

Formula

C27H36O5

CAS No.
SMILES

C[C@]1([C@@]([C@@H](CC)C)(O1)[H])[C@]2([C@@H](/C=C/C=C/C=C/C(O)=O)[C@]3([C@](C=C2C)(CC(C(OC)=O)=CC3)[H])[H])[H]

Structure Classification
Initial Source

Cladobotryum sp.

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cladobotric acid H
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HY-N19184
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