D-Erythro-sphingosine-1-phosphate
D-Erythro-sphingosine-1-phosphate is a phosphorylated sphingoid base and catabolic intermediate. As a component of the intracellular second messenger system, D-Erythro-sphingosine-1-phosphate induces rapid translocation of calcium ions in fibroblasts and acts as a mitogen. D-Erythro-sphingosine-1-phosphate also effectively inhibits the motility of melanoma cells, and can be used in the research of melanoma and other related diseases.
For research use only. We do not sell to patients.
- CAS No.: 528852-49-5
- Formula: C18H38NO5P
- Molecular Weight:379.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
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Biological Activity
D-Erythro-sphingosine-1-phosphate potently induces mitogenic activity in Swiss 3T3 fibroblasts[1].
D-Erythro-sphingosine-1-phosphate rapidly induces calcium release from intracellular stores in unspecified cells[1].
D-Erythro-sphingosine-1-phosphate (10 nM) inhibits motility of melanoma cells, while sphingosine has no effect at this concentration[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 528852-49-5
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Molecular Weight 379.48
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Formula C18H38NO5P
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SMILES
[C@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)(COP(=O)(O)O)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D-Erythro-sphingosine-1-phosphate Related Classifications
HY-184878 Related Classifications
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