D-myo-Inositol-1,3,4-triphosphate sodium
D-myo-Inositol-1,3,4-triphosphate (sodium) is one of the inositol oligophosphate isomers implicated in signal transduction. D-myo-Inositol-1,3,4-triphosphate (sodium) acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase cellular level of Ins(3,4,5,6)-P4, thereby inhibiting calcium-activated chloride channels. D-myo-Inositol-1,3,4-triphosphate (sodium) can be regulated by the levels of cytosolic free calcium.
For research use only. We do not sell to patients.
- Formula: C6H12Na3O15P3
- Molecular Weight:486.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
Chemical Information
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Molecular Weight 486.04
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Formula C6H12Na3O15P3
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SMILES
O[C@H]1[C@H]([C@@H]([C@H]([C@@H]([C@H]1OP(O)(O[Na])=O)OP(O)(O[Na])=O)O)O)OP(O)(O[Na])=O
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Synonyms
Ins(1,3,4)-P3 sodium; 1,3,4-IP3 sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lew, P. D., et al., (1986). The role of cytosolic free calcium in the generation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in HL-60 cells. Differential effects of chemotactic peptide receptor stimulation at distinct Ca2+ levels. The Journal of biological chemistry, 261(28), 13121–13127. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D-myo-Inositol-1,3,4-triphosphate sodium Related Classifications
HY-175387 Related Classifications
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