Dacomitinib metabolite M1/2
Dacomitinib metabolite M1/2 is a potent inhibitor of both wild-type (WT) EGFR and the T790M mutation, demonstrating significant activity against acquired resistance mechanisms in EGFR-mutant non-small-cell lung cancer (NSCLC).
For research use only. We do not sell to patients.
- CAS No.: 1262034-38-7
- Formula: C27H32ClFN6O4S
- Molecular Weight:591.10
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
Chemical Information
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CAS No. 1262034-38-7
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Molecular Weight 591.10
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Formula C27H32ClFN6O4S
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SMILES
COC(C(NC(CC(SC[C@H](N)C(O)=O)CN1CCCCC1)=O)=C2)=CC3=C2C(NC4=CC(Cl)=C(C=C4)F)=NC=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)