(E/Z)-Daporinad hydrochloride
Based on 1 publication(s) in Google Scholar
(E/Z)-Daporinad hydrochloride ((E/Z)-FK866 hydrochloride) is a potent inhibitor of nicotinamide phosphoribose transferase (NAMPT). (E/Z)-Daporinad hydrochloride induces apoptosis by specifically inhibiting NAMPT to gradually deplete intracellular NAD+. (E/Z)-Daporinad hydrochloride can be used in the study of cancer biology and inflammatory diseases.
For research use only. We do not sell to patients.
- CAS No.: 1785666-54-7
- Formula: C24H30ClN3O2
- Molecular Weight:427.97
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) (E/Z)-Daporinad hydrochloride
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Biological Activity
Chemical Information
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CAS No. 1785666-54-7
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Molecular Weight 427.97
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Formula C24H30ClN3O2
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SMILES
O=C(N1CCC(CC1)CCCCNC(/C=C/C2=CN=CC=C2)=O)C3=CC=CC=C3.Cl
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Synonyms
(E/Z)-FK866 hydrochloride; (E/Z)-APO866 hydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Signal Transduct Target Ther
High mtDNA content identifies oxidative phosphorylation-driven acute myeloid leukemias and represents a therapeutic vulnerability. [Abstract]2025 Jul 14;10(1):222. PMID: 40653487
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)